Bepc, Inc has an open position for a Research Associate II in South San Francisco, CA!!
W2 Contract 3 years
Pay and Benefits-$38-$44 an hour-Medical, Dental, Vision, Paid Life Insurance
We are seeking a highly motivated contractor to support discovery efforts in the Macrocycle Discovery Group within the Peptide Therapeutics Department.
The successful candidate will contribute to the identification of novel macrocyclic peptides using in vitro selection platforms and will play a key role in assay development, high-throughput screening, and data analysis for early drug discovery programs.
Key Responsibilities:
Conduct in vitro selection campaigns using mRNA and/or phage display technologies to discover active macrocyclic peptides targeting high-priority therapeutic proteins. Handle phage libraries, including amplification, titration, panning, and rescue procedures.
Design and execute ELISA-based binding assays for hit validation and screening. Utilize laboratory automation and high-throughput screening (HTS) techniques to enable efficient assay setup, sample processing, and reagent preparation.
Analyze next-generation sequencing (NGS) results using internal bioinformatics tools to identify early hits and guide selection campaign progression.
Test the incorporation and expression of non-canonical amino acid monomers to enhance library diversity through genetic code expansion. Maintain and manage complex reagent inventories used across multiple preclinical discovery platforms.
Collaborate cross-functionally with scientists in biochemistry, screening, and informatics to support project goals and timelines.
Qualifications:
B.S., M.S., or equivalent degree in Biochemistry, Molecular Biology, Chemical Biology, or a related discipline with relevant lab-based experience.
Hands-on experience with in vitro display technologies, particularly mRNA display and/or phage display (including phage propagation and selection).
Proficiency in ELISA, western blot, and high-throughput screening methods.
Familiarity with NGS data analysis and experience with laboratory automation platforms.
Strong attention to detail, excellent organizational skills, and ability to work both independently and as part of a collaborative team.
JRN: 2127 We are seeking a dedicated and detail-oriented Personal Assistant to manage the day-to-day life, household support, and extensive travel to a Grammy-winning pop artist. This is a high-touch, fast-paced role ideal for someone who has experience supporting touring...
...Our client, a high-end interiors brand is searching to hire a full-time Warehouse Manager to join their team! MUST HAVE EXPERIENCE WITH: luxury goods, furniture, home dcor, or textile industries or CPG Brand Work Environment: This role is based in a warehouse...
You will play a pivotal role in overseeing and optimizing the day-to-day activities to ensure efficiency and productivity. Your primary responsibilities will revolve around managing personnel, implementing strategic processes, and sustaining a positive work culture within...
...The Underwriter I position is responsible for working with Underwriting, Data, Account Managers, and producers to prepare proposal requests and obtain and analyze carrier quotes. You will also input & analyze data from various automation systems. It also works collaboratively...
...Triumphant Nerd is looking for a Senior Robotics Software Engineer to lead motion planning and control systems for high-precision, industrial pick-and-place robotic arms. Youll work hands-on with cutting-edge tech, contribute to a real-time control stack, and collaborate...